56 research outputs found
IoT for Global Development to Achieve the United Nations Sustainable Development Goals: The New Scenario After the COVID-19 Pandemic
COVID-19 has not affected all countries equally: developing countries have been more disadvantaged by the pandemic. Regarding global development, the COVID-19 pandemic has forced a step back in the path to attaining the Sustainable Development Goals (SDGs). The SDGs most negatively affected by the pandemic are identified here: education, health, and work. Then using the SDGs as a reference, this research explores the new challenges faced by developing countries and the impact of the Internet of Things (IoT) after COVID-19's emergence. IoT solutions carried out in developing countries during the pandemic have been identified and reviewed. Successful Internet of Things for Development (IoT4D) projects, in relation to the SDGs, are highlighted. New social and technical challenges that have emerged for the IoT4D as a consequence of the pandemic are then studied. This work concludes that the future of IoT4D in the wake of COVID-19 should focus on the use of low-cost IoT devices for the SDGs most affected by the pandemic. After an exhaustive study, the Intelligent Internet of Things (IIoT) has been determined to be a key actor in the pandemic's wake, with a leading role in the health sector. The proposed approach includes an extensive study of the new role of the IoT4D for achieving the SDGs in our forever changed world.This work was supported by the European Commission through Urban Innovative Actions of the EPIU Getafe Project under Grant UIA04-212. The work of Ascensión López-Vargas was supported by the University of Jaén, ``Ayudas de la EDUJA para la realización de estancias para la obtención de Mención Internacional,'' in 2019. The work of Agapito Ledezma was supported by the Agencia Estatal de Investigación (AEI) under Grant RTI2018-096036-B-C22/AEI/10.13039/501100011033. The work of Araceli Sanchis was supported by the Agencia Estatal de Investigación (AEI) under Grant PID2019-104793RB-C31/AEI/10.13039/501100011033
Patients' perceptions of the potential of breathing training for asthma: a qualitative study.
Poor symptom control is common in asthma. Breathing training exercises may be an effective adjunct to medication; it is therefore important to understand facilitators and barriers to uptake of breathing training exercises
Improved Biomedical and Psychological Outcomes 1 Year After Structured Education in Flexible Insulin Therapy for People With Type 1 Diabetes: The U.K. DAFNE experience
OBJECTIVEdDAFNE (Dose Adjustment For Normal Eating), a structured education program
in flexible insulin therapy, has been widely adopted in the U.K. after validation in a randomized
trial. To determine benefits in routine practice, we collected biomedical and
psychological data from all participants attending during a 12-month period.
RESEARCH DESIGN AND METHODSdHbA1c, weight, self-reported hypoglycemia
awareness, severe hypoglycemia frequency, PAID (Problem Areas In Diabetes), HADS (Hospital
Anxiety and Depression Scale), and EuroQol Group 5-Dimension Self-Report Questionnaire
scores were recorded prior to DAFNE and after 1 year.
RESULTSdComplete baseline and follow-up HbA1c data were available for 639 (54.9%) of
1,163 attendees. HbA1c fell from 8.51 6 1.41 (mean 6 SD) to 8.24 6 1.29% (difference 0.27
[95% CI 0.16–0.38]; P , 0.001), with a greater mean fall of 0.44% from baseline HbA1c .8.5%.
Severe hypoglycemia rate fell from 1.7 6 8.5 to 0.6 6 3.7 episodes per person per year (1.1 [0.7–
1.4]) and hypoglycemia recognition improved in 43% of those reporting unawareness. Baseline
psychological distress was evident, with a PAID score of 25.2 and HADS scores of 5.3 (anxiety)
and 4.8 (depression), falling to 16.7 (8.5 [6.6–10.4]), 4.6 (0.7 [0.4–1.0]), and 4.2 (0.6 [0.3–0.8]),
respectively (all P , 0.001 at 1 year). Clinically relevant anxiety and depression (HADS $8) fell
from 24.4 to 18.0% and 20.9 to 15.5%, respectively.
CONCLUSIONSdA structured education program delivered in routine clinical practice not
only improves HbA1c while reducing severe hypoglycemia rate and restoring hypoglycemia
awareness but also reduces psychological distress and improves perceived well-being
A Latin American Perspective to Agricultural Ethics
The mixture of political, social, cultural and economic environments in Latin America, together with the enormous diversity in climates, natural habitats and biological resources the continent offers, make the ethical assessment of agricultural policies extremely difficult. Yet the experience gained while addressing the contemporary challenges the region faces, such as rapid urbanization, loss of culinary and crop diversity, extreme inequality, disappearing farming styles, water and land grabs, malnutrition and the restoration of the rule of law and social peace, can be of great value to other regions in similar latitudes, development processes
and social problems. This chapter will provide a brief overview of these challenges from the perspective of a continent that is exposed to the consequences of extreme inequality in multiple dimensions and conclude by arguing for the need to have a continuous South-South dialogue on the challenges of establishing socially and environmentally sustainable food systems
Rationale for BepiColombo Studies of Mercury's Surface and Composition
BepiColombo has a larger and in many ways more capable suite of instruments relevant for determination of the topographic, physical, chemical and mineralogical properties of Mercury's surface than the suite carried by NASA's MESSENGER spacecraft. Moreover, BepiColombo's data rate is substantially higher. This equips it to confirm, elaborate upon, and go beyond many of MESSENGER's remarkable achievements. Furthermore, the geometry of BepiColombo's orbital science campaign, beginning in 2026, will enable it to make uniformly resolved observations of both northern and southern hemispheres. This will offer more detailed and complete imaging and topographic mapping, element mapping with better sensitivity and improved spatial resolution, and totally new mineralogical mapping. We discuss MESSENGER data in the context of preparing for BepiColombo, and describe the contributions that we expect BepiColombo to make towards increased knowledge and understanding of Mercury's surface and its composition. Much current work, including analysis of analogue materials, is directed towards better preparing ourselves to understand what BepiColombo might reveal. Some of MESSENGER's more remarkable observations were obtained under unique or extreme conditions. BepiColombo should be able to confirm the validity of these observations and reveal the extent to which they are representative of the planet as a whole. It will also make new observations to clarify geological processes governing and reflecting crustal origin and evolution. We anticipate that the insights gained into Mercury's geological history and its current space weathering environment will enable us to better understand the relationships of surface chemistry, morphologies and structures with the composition of crustal types, including the nature and mobility of volatile species. This will enable estimation of the composition of the mantle from which the crust was derived, and lead to tighter constraints on models for Mercury's origin including the nature and original heliocentric distance of the material from which it formed.Peer reviewe
Spatial navigation deficits — overlooked cognitive marker for preclinical Alzheimer disease?
Detection of incipient Alzheimer disease (AD) pathophysiology is critical to identify preclinical individuals and target potentially disease-modifying therapies towards them. Current neuroimaging and biomarker research is strongly focused in this direction, with the aim of establishing AD fingerprints to identify individuals at high risk of developing this disease. By contrast, cognitive fingerprints for incipient AD are virtually non-existent as diagnostics and outcomes measures are still focused on episodic memory deficits as the gold standard for AD, despite their low sensitivity and specificity for identifying at-risk individuals. This Review highlights a novel feature of cognitive evaluation for incipient AD by focusing on spatial navigation and orientation deficits, which are increasingly shown to be present in at-risk individuals. Importantly, the navigation system in the brain overlaps substantially with the regions affected by AD in both animal models and humans. Notably, spatial navigation has fewer verbal, cultural and educational biases than current cognitive tests and could enable a more uniform, global approach towards cognitive fingerprints of AD and better cognitive treatment outcome measures in future multicentre trials. The current Review appraises the available evidence for spatial navigation and/or orientation deficits in preclinical, prodromal and confirmed AD and identifies research gaps and future research priorities
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